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Synthetic lethality

Showing 1 - 25 of 962
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Solid Tumor, ARID1A Gene Mutation Trial in Greenville (Tazemetostat)

Suspended
  • Solid Tumor
  • ARID1A Gene Mutation
  • Greenville, South Carolina
    Prisma Health Cancer Institute
Jan 10, 2023

Mesothelioma, Uveal Melanoma, Renal Cell Carcinoma Trial in Gainesville, Miami, Orlando (Niraparib)

Completed
  • Mesothelioma
  • +3 more
  • Gainesville, Florida
  • +2 more
Jan 4, 2023

Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL) Trial in United Kingdom (SRA737)

Completed
Has Results
  • Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
  • Sutton, London, United Kingdom
  • +14 more
Mar 9, 2022

Sarcoma, Sarcoma,Soft Tissue, Sarcoma of Bone Trial in Shanghai (Camrelizumab and fluzoparib with concurrent stereotactic body

Recruiting
  • Sarcoma
  • +2 more
  • Camrelizumab and fluzoparib with concurrent stereotactic body radiotherapy (SBRT)
  • Shanghai, Shanghai, China
    Ruijin Hospital, Shanghai Jiao Tong University, School of Medici
Oct 3, 2023

Invasive Lobular Breast Carcinoma, ER+ Breast Cancer, HER2-negative Breast Cancer Trial in Belgium, France (Entrectinib,

Recruiting
  • Invasive Lobular Breast Carcinoma
  • +2 more
  • Brussels, Belgium
  • +9 more
May 4, 2022

Mesothelioma, Non Small Cell Lung Cancer, Malignant Peripheral Nerve Sheath Tumors Trial in United States (MRTX1719)

Recruiting
  • Mesothelioma
  • +5 more
  • Denver, Colorado
  • +5 more
Aug 8, 2022

Brain Tumor Trial in Rochester (Brain Surgery)

Recruiting
  • Brain Neoplasm
  • Brain Surgery
  • Rochester, Minnesota
    Mayo Clinic in Rochester
Jan 17, 2023

Advanced or Metastatic Solid Tumor, Liver Failure Trial in United States (Sacituzumab Govitecan-hziy)

Recruiting
  • Advanced or Metastatic Solid Tumor
  • Liver Failure
  • Sacituzumab Govitecan-hziy
  • Long Beach, California
  • +5 more
Jan 6, 2023

NSCLC, EGF-R Positive NSCLC Trial in Wuxi (Parimparib, Chemotherapy drug, Targeted Therapy Agent)

Recruiting
  • Carcinoma, Non-Small-Cell Lung
  • EGF-R Positive Non-Small Cell Lung Cancer
  • Wuxi, Jiangsu, China
    Affiliated Hospital of Jiangnan University
Jan 30, 2023

Endometrial Cancer, Serous Adenocarcinoma, Uterine Tumor Trial (Niraparib oral capsule)

Not yet recruiting
  • Endometrial Cancer
  • +2 more
  • Niraparib oral capsule
  • (no location specified)
Oct 31, 2022

Ovarian Cancer Trial in Chengdu (Yangzheng Xiaoji, Niraparib)

Not yet recruiting
  • Ovarian Cancer
  • Chengdu, Sichuan, China
    Sicchuan cancer hospital
Nov 30, 2022

Solid Tumor Trial in United States (IDE397, Docetaxel, Paclitaxel)

Recruiting
  • Solid Tumor
  • Scottsdale, Arizona
  • +10 more
Jul 20, 2022

MDD Trial in Eatontown (CYB003, Psychotherapy, Placebo)

Recruiting
  • Major Depressive Disorder
  • Eatontown, New Jersey
    Clinilabs Drug Development Corporation
Jul 11, 2022

Locally Advanced or Metastatic Solid Tumors, Genes, BRCA 1 Trial in Worldwide (Avelumab, Talazoparib)

Active, not recruiting
  • Locally Advanced or Metastatic Solid Tumors
  • Genes, BRCA 1
  • Palo Alto, California
  • +89 more
Jan 18, 2023

Urothelial Cancer Trial in Spain (Niraparib plus Cabozantinib)

Recruiting
  • Urothelial Cancer
  • Niraparib plus Cabozantinib
  • Barcelona, Cataluña, Spain
  • +10 more
Feb 8, 2022

Avelumab in Combination With Talazoparib Will be Investigated in Patients With Locally Advanced (Primary or Recurrent) or

Completed
  • Avelumab in Combination With Talazoparib Will be Investigated in Patients With Locally Advanced (Primary or Recurrent) or Metastatic Solid Tumors
  • Avelumab Phase 1b
  • +3 more
  • Fayetteville, Arkansas
  • +57 more
Jan 18, 2023

Cervical Cancer Trial in Chongqing (niraparib combined with brivanib, niraparib combined with toripalimab)

Recruiting
  • Cervical Cancer
  • niraparib combined with brivanib
  • niraparib combined with toripalimab
  • Chongqing, Chongqing, China
    Chongqing Cancer Hospital
May 19, 2021

Ovarian Cancer Trial

Not yet recruiting
  • Ovarian Cancer
    • (no location specified)
    Oct 13, 2022

    Advanced Ovarian Cancer, Primary Peritoneal Cancer, Advanced Breast Cancer Trial run by the NCI (BMN 673)

    Completed
    Has Results
    • Advanced Ovarian Cancer
    • +3 more
    • BMN 673
    • Bethesda, Maryland
      National Institutes of Health Clinical Center, 9000 Rockville Pi
    Feb 2, 2021

    Optimal Strategy for Repair of Type A Acute Aortic Dissection

    Not yet recruiting
    • Aortic Dissection
    • Conservative TAAAD-R
    • Extensive TAAAD-R
    • (no location specified)
    Jun 20, 2023

    Cancer, Solid Tumor Trial in San Francisco (Personalized Synthetic Long Peptide Vaccine)

    Enrolling by invitation
    • Cancer
    • Solid Tumor
    • Personalized Synthetic Long Peptide Vaccine
    • San Francisco, California
      Quest Clinical Research
    Feb 20, 2023

    Efficacy and Adverse Effects of Olaparib in Ovarian Cancer.

    Enrolling by invitation
    • Ovarian Cancer
      • Xi'an, Shaanxi, China
        The First Affliated Hospital of Xi'an Jiaotong University
      Mar 23, 2022

      Acute Kidney Injury, Surgery-Complications, Nephropathy Trial in Seoul

      Completed
      • Acute Kidney Injury
      • +2 more
        • Seoul, Korea, Republic of
          Seoul National University Hospital
        Aug 3, 2023

        Nicotine Dependence, Nicotine Vaping Trial in San Francisco ((S)-Nicotine, (R)- nicotine, Racemic nicotine)

        Not yet recruiting
        • Nicotine Dependence
        • Nicotine Vaping
        • San Francisco, California
          Zuckerberg San Francisco General Hospital (ZSFG)
        Jul 17, 2023

        Colorectal Cancer (CRC)

        Recruiting
        • Colorectal Neoplasms
        • No intervention for this trial.
        • Scottsdale, Arizona
        • +8 more
        Aug 15, 2022